Bacteria, Antibiotics and Resistance

Lesson 5

These videos describe the chemistry of antibiotic drug development.

 
 

What is Medicinal Chemistry?

One needs to consider a number of factors when developing a new antibiotic. This video introduces the subject of medicinal chemistry and pharmacokinetics.

 

Drug Development

This video introduces how drugs are developed. The concept of Structure-Activity relationships are described.

 

STRUCTURE-ACTIVITY: Quinolones

Structure-activity relationships can be used to design an antibiotic. Quinolones are used as an example..

 

BEta-LACTAMS STRUCTURE-ACTIVITY

One of the largest classes of antibiotics are the beta-lactams (penicillin, for example). How we can use the structure of beta-lactams to develop new compounds is described.

 

New Antibiotic Drug Discovery

New classes of antibiotics are very needed. This video describes how we can discover new antibiotics.

 

Test your knowledge of Lesson 5 here!